Titov V N
Vopr Med Khim. 1997 Jul-Aug;43(4):195-207.
System of lipoproteins serves for the transport of fatty acids in the blood. Triacylglycerols are the transport form of saturated (mono-unsaturated and trans-forms) fatty acids forming crystal phase. Phospolipids and cholesterol ethers are transport forms of polyunsaturated acids in the polar and crystal phases, respectively. Even in the forms of complex lipids saturated and polyunsaturated fatty acids are transported in the blood by various apoproteins. ApoB-48 transports saturated fatty acids to hepatocytes in the form of chilomicrons. ApoA-1 transports transports polyunsaturated fatty acids directly to cells including hepatocytes. ApoA-100 contains two lipid binding domains. It transports saturated fatty acids and their cholesterol ethers associated with the third and fifth domains, respectively. For the structural function polyunsaturated fatty acids are transported by ApoA-1 high density lipoproteins in the polar phase and they penetrate into cells via phospholipid re-esterification.
脂蛋白系统用于在血液中运输脂肪酸。三酰甘油是形成晶相的饱和（单不饱和及反式）脂肪酸的运输形式。磷脂和胆固醇醚分别是多不饱和酸在极性相和晶相中的运输形式。即使以复合脂质的形式，饱和脂肪酸和多不饱和脂肪酸在血液中也由各种载脂蛋白运输。载脂蛋白B-48以乳糜微粒的形式将饱和脂肪酸运输到肝细胞。载脂蛋白A-1将多不饱和脂肪酸直接运输到包括肝细胞在内的细胞。载脂蛋白A-100包含两个脂质结合结构域。它分别通过第三和第五结构域运输饱和脂肪酸及其胆固醇醚。对于结构功能而言，多不饱和脂肪酸由载脂蛋白A-1高密度脂蛋白在极性相中运输，并通过磷脂再酯化进入细胞。
