Abe T, Matsumoto K, Iida M, Hayashi M, Sanno N, Osamura R Y
Department of Neurosurgery, Showa University School of Medicine, Tokyo, Japan.
Surg Neurol. 1997 Oct;48(4):389-94. doi: 10.1016/s0090-3019(97)00002-5.
Although the pituitary gland is known to harbor metastatic deposits, metastasis from a carcinoid tumor is extremely rare. Metastasis to a pituitary adenoma also is an infrequent occurrence.
A case of malignant carcinoid tumor of the anterior mediastinum with metastasis to a prolactin-secreting pituitary adenoma is presented in this 46-year-old woman. This metastatic pituitary tumor demonstrated a high proliferative potential.
To our knowledge, this case represents the first documentation of metastasis from a malignant carcinoid tumor to a pituitary adenoma.