Murray J A
Department of Medicine, University of Iowa, Iowa City, USA.
Clin Lab Med. 1997 Sep;17(3):445-64.
The detection rate of celiac disease greatly underestimates its prevalence. This is the result of lack of awareness of the many manifestations of the condition and the requirement for at least one small intestinal biopsy for diagnosis. The advent of effective serologic tests for the condition heralds a new era of non-invasive testing. The clinical utility and acceptance of these tests is limited by a lack of standardization of both the techniques used and variability of reference ranges quoted.
乳糜泻的检出率大大低估了其患病率。这是由于对该疾病的多种表现缺乏认识，以及诊断需要至少进行一次小肠活检。针对该疾病的有效血清学检测的出现预示着无创检测的新时代。这些检测的临床实用性和认可度受到所用技术缺乏标准化以及所引用参考范围变异性的限制。
