溶组织内阿米巴与肠上皮细胞之间的相互作用涉及寄生虫表面表达的一种CD44交叉反应蛋白。
Interaction between Entamoeba histolytica and intestinal epithelial cells involves a CD44 cross-reactive protein expressed on the parasite surface.
作者信息
Renesto P, Sansonetti P J, Guillén N
机构信息
Unité de Pathogénie Microbienne Moléculaire, Institut National de la Santé et de la Recherche Médicale U389, Institut Pasteur, Paris, France.
出版信息
Infect Immun. 1997 Oct;65(10):4330-3. doi: 10.1128/iai.65.10.4330-4333.1997.
Abstract
This study shows that Entamoeba histolytica binds hyaluronic acid. The binding molecule was identified as an 80-kDa membrane protein and was recognized by anti-CD44 monoclonal antibodies. These data indicate that a CD44 cross-reacting adherence molecule is expressed on E. histolytica.
摘要
本研究表明，溶组织内阿米巴可结合透明质酸。结合分子被鉴定为一种80 kDa的膜蛋白，并可被抗CD44单克隆抗体识别。这些数据表明，溶组织内阿米巴表达一种与CD44交叉反应的黏附分子。
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