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颈椎前路手术后发生严重血管性水肿导致气道梗阻。

Severe angioedema causing airway obstruction after anterior cervical surgery.

作者信息

Krnacik M J, Heggeness M H

机构信息

Department of Orthopedic Surgery, Baylor College of Medicine, Houston, Texas, USA.

出版信息

Spine (Phila Pa 1976). 1997 Sep 15;22(18):2188-90. doi: 10.1097/00007632-199709150-00019.

Abstract

STUDY DESIGN

A case of severe postoperative angioedema after excision of cervical osteophyte is presented. Emergent tracheostomy was required.

OBJECTIVES

To discuss the etiologies, diagnosis, and management of this unusual cause of acute respiratory distress after an anterior cervical spinous procedure.

SUMMARY OF BACKGROUND DATA

To our knowledge, angioedema as a complication of cervical spine surgery has not been reported previously. The patient had no history of angioedema, was not receiving an acetyl choline esterase inhibitor, and had a normal C1-esterase-inhibitor level.

METHODS

The patient was a 61-year-old man with ankylosing spondylitis who, because of progressive dysphagia and choking episodes, underwent excision of a large C3-C4 osteophyte and anterior cervical discectomy and fusion. While in the postanesthesia care unit, the patient experienced massive edema of the tongue and neck, with associated difficulty breathing. Reexploration of the wound revealed a small (30 cc) hematoma, which was removed with no obvious benefit to the patient, who ultimately required a tracheotomy.

RESULTS

The patient was managed with intravenous corticosteroids. The tracheotomy tube was removed without incident after 7 days. The patient noted decreased neck pain and dramatic improvement in his ability to swallow postoperatively. He has had no further incidents of angioedema, to date.

CONCLUSION

Angioedema should be considered in the differential diagnosis in patients with upper extremity respiratory obstruction after anterior surgery of the cervical spine.

摘要

研究设计

报告一例颈椎骨赘切除术后严重的血管性水肿病例,患者需要紧急气管切开术。

目的

探讨颈椎前路手术后这种导致急性呼吸窘迫的不寻常病因的病因、诊断及处理方法。

背景资料总结

据我们所知,血管性水肿作为颈椎手术的并发症此前未见报道。该患者无血管性水肿病史,未接受乙酰胆碱酯酶抑制剂治疗,C1酯酶抑制剂水平正常。

方法

患者为一名61岁的强直性脊柱炎男性,因进行性吞咽困难和呛咳发作,接受了C3-C4大型骨赘切除及颈椎前路椎间盘切除融合术。在麻醉后护理单元时,患者出现舌部和颈部大量水肿,并伴有呼吸困难。再次探查伤口发现一个小(30 cc)血肿,将其清除后对患者并无明显益处,患者最终需要进行气管切开术。

结果

患者接受静脉注射皮质类固醇治疗。7天后气管切开管顺利拔除。患者术后颈部疼痛减轻,吞咽能力显著改善。迄今为止,他未再发生血管性水肿事件。

结论

颈椎前路手术后出现上肢呼吸梗阻的患者,鉴别诊断时应考虑血管性水肿。

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