Weiss D, Coccaro E F
Department of Psychiatry, Hahnemann School of Medicine, Allegheny University of the Health Sciences, Philadelphia, Pennsylvania, USA.
Psychiatr Clin North Am. 1997 Sep;20(3):563-79. doi: 10.1016/s0193-953x(05)70330-0.
This article reviews the research data regarding human neuroendocrine systems and suicidal behavior. Special emphasis is placed on pharmacochallenge studies. Such studies uniquely allow for functional assessment of neuroendocrine parameters in living subjects. Serotonergic mechanisms have been the most fruitful areas of research. While discussing the major areas of controversy, theoretical approaches to integration are offered.
本文综述了关于人类神经内分泌系统与自杀行为的研究数据。特别强调了药物激发试验研究。此类研究独特地允许对活体受试者的神经内分泌参数进行功能评估。血清素能机制一直是最富有成果的研究领域。在讨论主要争议领域的同时,还提供了整合的理论方法。