转移至虹膜的尤因肉瘤。
Ewing sarcoma metastatic to the iris.
作者信息
Gündüz K, Shields J A, Shields C L, De Potter P, Wayner M J
机构信息
Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA.
出版信息
Am J Ophthalmol. 1997 Oct;124(4):550-2. doi: 10.1016/s0002-9394(14)70873-6.
PURPOSE
To report a case of Ewing sarcoma metastatic to the iris.
METHODS
A 19-year-old woman with metastatic Ewing sarcoma of the femur developed a diffuse, fluffy iris mass with a pseudohypopyon in the left eye. A fine-needle aspiration biopsy confirmed iris metastasis, and external beam radiotherapy was given to the affected eye.
RESULTS
The iris mass responded initially to external beam radiotherapy and ongoing chemotherapy with vincristine, cyclophosphamide, doxorubicin, etoposide, and ifosfamide but recurred 5 months later. Subsequent radiotherapy with an iodine 125 plaque achieved further resolution of the iris tumor.
CONCLUSIONS
Ewing sarcoma can rarely metastasize to the iris. The diagnosis can be confirmed by fine-needle aspiration biopsy. Plaque radiotherapy is a therapeutic alternative.
目的
报告1例发生虹膜转移的尤因肉瘤病例。
方法
一名19岁患有股骨转移性尤因肉瘤的女性，左眼出现弥漫性、絮状虹膜肿物并伴有假性前房积脓。细针穿刺活检证实为虹膜转移，对患眼进行了外照射放疗。
结果
虹膜肿物最初对外照射放疗及持续使用长春新碱、环磷酰胺、多柔比星、依托泊苷和异环磷酰胺化疗有反应，但5个月后复发。随后使用碘125敷贴器进行放疗使虹膜肿瘤进一步消退。
结论
尤因肉瘤很少转移至虹膜。细针穿刺活检可确诊。敷贴器放疗是一种治疗选择。
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