十二指肠酸化对清醒猫胃黏液及胃酸分泌的影响。
Effect of duodenal acidification on gastric mucus and acid secretion in conscious cats.
作者信息
Vagne M, Perret G
出版信息
Digestion. 1976;14(4):332-41. doi: 10.1159/000197949.
In cats with gastric fistulae and Heidenhein pouches, the effect of acid entering the duodenum on secretion of acid, pepsin, and mucus from the Heidenhain pouch during maximal acid stimulation with pentagastrin or histamine, was studied. Duodenal acidification produced stimulation of pepsin and mucus secretion comparable to that induced by exogenous hormones (secretin and the combination of secretin with cholecystokinin). In addition, duodenal acidification caused an increase in acid secretion, thus suggesting that, in addition to secretin and cholecystokinin, a factor that stimulates acid secretion was also released by acid.
在患有胃瘘和海登海因小胃的猫中，研究了在使用五肽胃泌素或组胺进行最大酸刺激时，酸进入十二指肠对海登海因小胃中酸、胃蛋白酶和黏液分泌的影响。十二指肠酸化对胃蛋白酶和黏液分泌的刺激作用与外源性激素（促胰液素以及促胰液素与缩胆囊素的组合）诱导的作用相当。此外，十二指肠酸化导致酸分泌增加，因此表明，除促胰液素和缩胆囊素外，酸还释放出一种刺激酸分泌的因子。
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