Melamed E, Rachmilewitz E A, Reches A, Lavy S
J Neurol Neurosurg Psychiatry. 1976 Apr;39(4):320-4. doi: 10.1136/jnnp.39.4.320.
Two patients with untreated polycythaemia vera developed intracranial internal carotid arterial occlusion followed by monocular blindness and the characteristic features of ipsilateral cavernous sinus thrombosis. Primary septic source and signs of systemic infection were absent. It is suggested that the predisposing factors in this unusual syndrome were hyperviscosity and venous sludging induced by the basic haematological disorder and progression of the thrombotic process within the internal carotid artery towards its intracavernous portion with occlusion of the ophthalmic artery and of the arterial branches which supply the walls of the sinus.
两名未经治疗的真性红细胞增多症患者发生了颅内颈内动脉闭塞，随后出现单眼失明以及同侧海绵窦血栓形成的特征性表现。未发现原发性感染源和全身感染迹象。提示这一罕见综合征的诱发因素是基础血液系统疾病所致的高黏滞血症和静脉淤滞，以及颈内动脉内血栓形成过程向其海绵窦段进展，导致眼动脉及供应海绵窦壁的动脉分支闭塞。
