Khuri S F, Daley J, Henderson W, Hur K, Gibbs J O, Barbour G, Demakis J, Irvin G, Stremple J F, Grover F, McDonald G, Passaro E, Fabri P J, Spencer J, Hammermeister K, Aust J B
Brockton/West Roxbury VA Medical Center, West Roxbury, MA 02132, USA.
J Am Coll Surg. 1997 Oct;185(4):315-27.
The National Veterans Affairs Surgical Risk Study was designed to collect reliable, valid data on patient risk and outcomes for major surgery in the Veterans Health Administration and to report comparative risk-adjusted postoperative mortality rates for surgical services in Veterans Health Administration.
This cohort study was conducted in 44 Veterans Affairs Medical Centers. Included were 87,078 major noncardiac operations performed under general, spinal, or epidural anesthesia between October 1, 1991, and December 31, 1993. The main outcomes measure was all-cause mortality within 30 days after the index procedure. Multivariable logistic regression risk-adjustment models for all operations and for eight surgical subspecialties were developed. Risk-adjusted surgical mortality rates were expressed as observed-to-expected ratios and were compared with unadjusted 30-day postoperative mortality rates.
Patient risk factors predictive of postoperative mortality included serum albumin level, American Society of Anesthesia class, emergency operation, and 31 additional preoperative variables. Considerable variability in unadjusted mortality rates for all operations was observed across the 44 hospitals (1.2-5.4%). After risk adjustment, observed-to-expected ratios ranged from 0.49 to 1.53. Rank order correlation of the hospitals by unadjusted and risk-adjusted mortality rates for all operations was 0.64. Ninety-three percent of the hospitals changed rank after risk adjustment, 50% by more than 5 and 25% by more than 10.
The Department of Veterans Affairs has successfully implemented a system for the prospective collection and comparative reporting of risk-adjusted postoperative mortality rates after major noncardiac operations. Risk adjustment had an appreciable impact on the rank ordering of the hospitals and provided a means for monitoring and potentially improving the quality of surgical care.
国家退伍军人事务部外科手术风险研究旨在收集关于退伍军人健康管理局(VHA)重大手术患者风险和结局的可靠、有效数据,并报告VHA外科服务经过风险调整后的术后死亡率比较情况。
这项队列研究在44家退伍军人事务医疗中心开展。纳入了1991年10月1日至1993年12月31日期间在全身麻醉、脊髓麻醉或硬膜外麻醉下进行的87078例重大非心脏手术。主要结局指标是索引手术(首次手术)后30天内的全因死亡率。针对所有手术和八个外科亚专业建立了多变量逻辑回归风险调整模型。风险调整后的手术死亡率以观察值与期望值之比表示,并与未调整的术后30天死亡率进行比较。
预测术后死亡率的患者风险因素包括血清白蛋白水平、美国麻醉医师协会分级、急诊手术以及另外31个术前变量。在44家医院中,所有手术的未调整死亡率存在显著差异(1.2% - 5.4%)。风险调整后,观察值与期望值之比在0.49至1.53之间。所有手术的未调整和风险调整后死亡率在各医院之间的等级相关系数为0.64。93%的医院在风险调整后改变了排名,50%的医院排名变化超过5位,25%的医院排名变化超过10位。
退伍军人事务部已成功实施了一个系统,用于前瞻性收集和比较报告重大非心脏手术后风险调整后的术后死亡率。风险调整对医院的排名顺序有显著影响,并为监测和潜在改善外科护理质量提供了一种手段。