Goszcz A, Grodzinska L, Kostka-Trebka E, Bieron K, Slawinski M, Jachym R
Acta Physiol Hung. 1996;84(4):415-6.
The stable prostacyclin analogue-iloprost and prostaglandin E1 (Alprostadil) showed a beneficial effect on activated platelets and leukocytes, and thrombocyte and leukocyte vessel interaction and damaged endothelium, improving microvascular perfusion and were useful in treatment of patients with peripheral arterial disease. The 4 weeks therapy with misoprostol caused a clinical improvement in all 14 patients and resulted in vasorelaxation and showed antiplatelet and fibrinolytic effects.
稳定的前列环素类似物伊洛前列素和前列腺素E1（前列地尔）对活化的血小板和白细胞、血小板与白细胞的血管相互作用以及受损的内皮显示出有益作用，改善了微血管灌注，对治疗外周动脉疾病患者有用。米索前列醇4周的治疗使所有14例患者的临床症状得到改善，导致血管舒张，并显示出抗血小板和纤溶作用。
