Mansoury B, Barbor P H, Feteih J, Rotimi V O
Department of Paediatrics, King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia.
West Afr J Med. 1997 Jul-Sep;16(3):195-8.
Salmonella infection in sickle cell disease patients is generally well-known but presentation as superficial abscess is relatively uncommon. Two sisters aged 4 1/2 and 6 years presented with superficial subcutaneous abscesses that were caused by the same strain of Salmonella enteriditis group C. Despite in vitro susceptibility with a MIC of 0.03 microgram/ml and an adequate dosage of ciprofloxacin there was a relapse with widespread dissemination of the same organism in the younger sister who subsequently developed multiple osteolytic infections. Change of treatment to chloramphenicol produced a cure in both patients.
镰状细胞病患者的沙门氏菌感染通常广为人知，但表现为浅表脓肿相对少见。两名分别为4岁半和6岁的姐妹出现了由同一株C群肠炎沙门氏菌引起的浅表皮下脓肿。尽管体外药敏显示最低抑菌浓度为0.03微克/毫升且环丙沙星剂量充足，但较年幼的妹妹仍出现复发，同一病原体广泛播散，随后发展为多处溶骨性感染。改用氯霉素治疗后两名患者均治愈。
