Jankovic J, Růzicka E
Parkinson's Disease Center and Movement Disorders Clinic, Baylor College of Medicine, Houston, Texas, USA.
Cas Lek Cesk. 1997 Jun 26;136(13):399-404.
This article is reviewing current knowledge of Tourette's syndrome (TS) including its clinical picture, pathophysiology, genetics and treatment. The semiology of TS is characterized with various types of motor and vocal tics and associated pathological behaviors as attention deficit hyperactivity disorder and obsessive-compulsive disorder. Recent pathophysiological and genetic data confirm organic character of the condition. Treatment strategies are proposed with regard to prevailing type of symptoms.
本文回顾了目前关于妥瑞氏症(TS)的知识,包括其临床表现、病理生理学、遗传学和治疗方法。TS的症状学特征为各种类型的运动性和发声性抽动以及相关的病理行为,如注意力缺陷多动障碍和强迫症。最近的病理生理学和遗传学数据证实了该病症的器质性特征。针对主要症状类型提出了治疗策略。