Breuninger H, Bogenschütz O, Konrad E, Rassner G
Universitäts-Hautklinik, Tübingen.
Hautarzt. 1997 Jul;48(7):496-9. doi: 10.1007/s001050050617.
A 65 year old male patient was diagnosed with hereditary hemorrhagic telangiectasia at 30. During recent years he has suffered frequent, almost daily, nose bleeds causing anemia and making several blood transfusions necessary. In the past 2-3 years, the patient has developed multiple squamous cell carcinomas on the face. These unusually large tumours were treated by micrographic surgery using paraffin sections and the defects dosed with a variety of flaps and grafts. Several solar keratoses were also removed. If hemostasis parameters are normal, skin surgery can be performed without hesitation in hereditary hemorrhagic telangiectasia.
一名65岁男性患者在30岁时被诊断为遗传性出血性毛细血管扩张症。近年来,他频繁鼻出血,几乎每天都有,导致贫血,需要多次输血。在过去的2至3年里,患者面部出现了多处鳞状细胞癌。这些异常大的肿瘤通过使用石蜡切片的显微外科手术进行治疗,缺损部位用各种皮瓣和移植物覆盖。还切除了几处日光性角化病。如果止血参数正常,在遗传性出血性毛细血管扩张症患者中可以毫不犹豫地进行皮肤手术。