Cardoni A A
University of Connecticut, Storrs, USA.
Conn Med. 1997 Sep;61(9):587-95.
This paper reviews the current clinical use of psychotropic drugs and suggests new directions for future drug development. The author reviews the contemporary pharmacotherapy of depression, anxiety disorders, schizophrenia, and bipolar disorder and summarizes current trends in the drug treatment of psychiatric aspects of HIV disease. The increasing use of combination pharmacotherapy is discussed, as well as the impact of pharmacokinetics in clinical psychopharmacology. The use of botanical products for psychiatric disorders and tobacco use in the psychiatric patient are also addressed. Current research is producing drugs that have greater specificity in their mechanism of action effecting faster clinical response with minimum adverse effects.
本文回顾了精神药物的当前临床应用，并提出了未来药物研发的新方向。作者回顾了抑郁症、焦虑症、精神分裂症和双相情感障碍的当代药物治疗方法，并总结了艾滋病病毒疾病精神方面药物治疗的当前趋势。文中讨论了联合药物治疗的日益广泛应用，以及药代动力学在临床精神药理学中的影响。还探讨了植物产品在精神疾病治疗中的应用以及精神病患者吸烟的问题。当前的研究正在生产作用机制具有更高特异性的药物，能带来更快的临床反应且副作用最小。
