Takami Y, Nakazawa T, Otsuka G, Tayama E, Ohashi Y, Sueoka A, Schima H, Schmallegger H, Wolner E, Nosé Y
Department of Surgery, Baylor College of Medicine, Houston, Texas, U.S.A.
Artif Organs. 1997 Oct;21(10):1132-6. doi: 10.1111/j.1525-1594.1997.tb00455.x.
A miniaturized pivot bearing-supported centrifugal blood pump (Gyro PI) has been developed as a long-term biventricular assist system (BiVAS). In this study we determined the anatomical configuration of this system using a bovine model. Under general anesthesia, a left lateral thoracotomy was performed to open the chest. Two Gyro PI-601 pumps for left and right assists were placed in the preperitoneal pocket by a subcostal abdominal incision. The left pump could be placed along the dome of the diaphragm just beneath the apex of the left ventricle. The right pump could be placed next to the left pump. The inlet and outlet ports of both pumps penetrated the diaphragm. The inlet port of the left pump, with a length of 55 mm, was inserted directly into the apex of the left ventricle. A woven Dacron graft (150 mm long, 11 mm inner diameter) was placed between the outlet port of the left pump and the descending aorta. As for the right pump, a 100 mm long and 120 degree angled inflow conduit was placed between the inlet port and the right ventricular infundibulum. The outlet port of the right pump was connected to the main trunk of the pulmonary artery using a 90 mm long, 11 mm inner diameter Dacron graft. We could perform biventricular assistance to confirm the anatomical feasibility of the Gyro implantable centrifugal BiVAS.
一种小型化的枢轴轴承支撑式离心血泵（Gyro PI）已被开发用作长期双心室辅助系统（BiVAS）。在本研究中，我们使用牛模型确定了该系统的解剖结构。在全身麻醉下，进行左外侧开胸术打开胸腔。通过肋下腹部切口将两个用于左右辅助的Gyro PI - 601泵置于腹膜前腔隙。左泵可沿膈肌穹窿置于左心室心尖下方。右泵可置于左泵旁边。两个泵的进出口均穿透膈肌。左泵的入口长55毫米，直接插入左心室心尖。在左泵出口与降主动脉之间放置一段编织涤纶移植物（长150毫米，内径11毫米）。至于右泵，在入口与右心室漏斗部之间放置一段长100毫米、呈120度角的流入导管。右泵的出口使用一段长90毫米、内径11毫米的涤纶移植物连接至肺动脉主干。我们能够进行双心室辅助以确认Gyro可植入式离心BiVAS的解剖可行性。
