Pérez J A, Silva R, Torres A, López B, Henning E, Pérez A
Instituto de Cirugía, Facultad de Medicina, Universidad Austral de Chile.
Rev Med Chil. 1997 Jan;125(1):43-8.
The choice of medical, radiation or surgical therapy for hyperthyroid diffuse goiter is still empirical.
To report a retrospective analysis of the surgical treatment of hyperthyroid goiter in a Regional Hospital in Chile.
The charts of 64 patients, 54 female, aged between 15 and 57 years old, operated between 1985 and 1995 were analyzed.
The indication for surgical treatment was failure of medical treatment in 59 patients and a big goiter causing mechanical compression in 3 patients. A subtotal thyroidectomy was done after an abbreviated surgical preparation. The mean weight of the resected glands was 65.9 g. Four patients had transient hypocalcemia and 4 had surgical wound seromas. After a mean follow up of 31 months, 77% of patients remain euthyroid, hyperthyroidism relapsed in 13.1% and 10% became hypothyroid.
Surgical treatment of hyperthyroid goiter is safe but the percentage of hyperfunction relapse is high.
对于甲状腺功能亢进性弥漫性甲状腺肿，选择药物、放射或手术治疗仍缺乏经验依据。
报告智利一家地区医院对甲状腺功能亢进性甲状腺肿手术治疗的回顾性分析。
分析了1985年至1995年间接受手术的64例患者的病历，其中女性54例，年龄在15至57岁之间。
手术治疗的指征为59例药物治疗失败，3例因巨大甲状腺肿导致机械性压迫。在简化手术准备后进行了甲状腺次全切除术。切除腺体的平均重量为65.9克。4例患者出现短暂性低钙血症，4例出现手术伤口血清肿。平均随访31个月后，77%的患者甲状腺功能正常，13.1%的患者甲亢复发，10%的患者出现甲状腺功能减退。
甲状腺功能亢进性甲状腺肿的手术治疗是安全的，但功能亢进复发率较高。
