Alternative (non-P-glycoprotein) mechanisms of drug resistance in non-Hodgkin's lymphoma.
作者信息
Dalton W S
机构信息
H. Lee Moffitt Cancer Center, University of South Florida, Tampa, USA.
出版信息
Hematol Oncol Clin North Am. 1997 Oct;11(5):975-86. doi: 10.1016/s0889-8588(05)70474-3.
PMID:9336726
Abstract
Drug resistance remains a significant obstacle to improving therapeutic outcome following treatment for malignant lymphoma. Eliminating P-glycoprotein as one mechanism of drug resistance may select for alternative, non-P-glycoprotein mechanisms of drug resistance. Understanding these alternative forms of drug resistance is imperative in order to improve therapy for NHL.
摘要
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