补骨脂素加紫外线A（PUVA）治疗后出现严重的皮肤疼痛。
Severe skin pain after PUVA treatment.
作者信息
Tegner E
出版信息
Acta Derm Venereol. 1979;59(5):467-70.
PMID:93376
Abstract
Severe skin pain lasting one or two months occurred in 8 of 210 patients treated with PUVA. The pain started 4--8 weeks after the initial dose, mostly about one week after discontinuation of the treatment. It was a prickling, burning pain, usually coming in bouts and confined to limited areas "deep under the skin". In some respects the pain was related to itching, but the patients could easily distinguish between the two sensations. A variety of drugs was tried, but none had any noteworthy effect on this peculiar pain.
摘要
210名接受补骨脂素加紫外线A（PUVA）治疗的患者中有8人出现了持续一到两个月的严重皮肤疼痛。疼痛在首次给药后4至8周开始，大多在治疗停止后约一周出现。这是一种刺痛、灼痛，通常呈阵发性发作，局限于“皮肤深层”的有限区域。在某些方面，疼痛与瘙痒有关，但患者能够轻松区分这两种感觉。尝试了多种药物，但没有一种对这种特殊疼痛有显著效果。
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