Critchley M
Department of Nuclear Medicine, Royal Liverpool University Hospital, UK.
Postgrad Med J. 1997 Jul;73(861):399-402. doi: 10.1136/pgmj.73.861.399.
The somatostatin analogue octreotide may be used in the diagnosis of carcinoid and other neuroendocrine tumours. Radionuclide scanning following intravenous injection of 111Indium-labelled octreotide (111In-DTPA-pentetreotide) provides a sensitive, non-invasive method of localising somatostatin-positive tumours. The technique may also be used to identify patients who may respond to 'cold' octreotide therapy and to monitor therapeutic efficacy.
生长抑素类似物奥曲肽可用于类癌和其他神经内分泌肿瘤的诊断。静脉注射111铟标记的奥曲肽(111In-DTPA-五肽胃泌素)后进行放射性核素扫描,为定位生长抑素阳性肿瘤提供了一种敏感、非侵入性的方法。该技术还可用于识别可能对“冷”奥曲肽治疗有反应的患者,并监测治疗效果。