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两例腰麻-硬膜外联合麻醉后马尾综合征病例。

Two cases of cauda equina syndrome following spinal-epidural anesthesia.

作者信息

Kubina P, Gupta A, Oscarsson A, Axelsson K, Bengtsson M

机构信息

Department of Anaesthesiology, Orebro Hospital Medical Center, Sweden.

出版信息

Reg Anesth. 1997 Sep-Oct;22(5):447-50. doi: 10.1016/s1098-7339(97)80032-6.

Abstract

BACKGROUND AND OBJECTIVES

Cauda equina syndrome (CES) is a well-known complication of spinal and epidural anesthesia. Previous reports have implicated lidocaine, chloroprocaine, and procaine in its etiology, but not bupivacaine.

METHODS

A 63-year-old man underwent transurethral resection of the prostrate for which he received bupivacaine with glucose intrathecally. Postoperative, he had difficulty in urination and defecation, and magnetic resonance imaging revealed spinal stenosis at the L1-L2 level. The second patient was a 70-year-old woman who underwent hip replacement surgery using a combined spinal-epidural technique. Postoperative, after 42 hours, when the epidural infusion of bupivacaine was stopped, the patient had difficulty in urination and defecation. No anatomical abnormality was found on magnetic resonance imaging.

RESULTS

The two patients developed cauda equina syndrome following bupivacaine with glucose injected spinally, and bupivacaine without glucose injected in a combined spinal-epidural technique.

CONCLUSIONS

This case report describes two cases of CES following the use of bupivacaine. The first patient had spinal stenosis which could explain this complication; however the explanation for CES in the second patient is uncertain and consequently speculative. We have discussed the possible contributing factors but believe that the etiology of CES in the second patient remains unknown.

摘要

背景与目的

马尾综合征(CES)是脊柱和硬膜外麻醉的一种已知并发症。既往报道认为利多卡因、氯普鲁卡因和普鲁卡因与该并发症的病因有关,但布比卡因与之无关。

方法

一名63岁男性接受经尿道前列腺切除术,术中接受了鞘内注射含葡萄糖的布比卡因。术后,他出现排尿和排便困难,磁共振成像显示L1-L2水平存在椎管狭窄。第二名患者是一名70岁女性,她采用腰麻-硬膜外联合技术进行了髋关节置换手术。术后42小时,当停止硬膜外输注布比卡因时,患者出现排尿和排便困难。磁共振成像未发现解剖学异常。

结果

两名患者在鞘内注射含葡萄糖的布比卡因以及在腰麻-硬膜外联合技术中注射不含葡萄糖的布比卡因后均发生了马尾综合征。

结论

本病例报告描述了两例使用布比卡因后发生CES的病例。首例患者存在椎管狭窄,这可以解释该并发症;然而,第二例患者发生CES的原因尚不确定,因此只是推测。我们讨论了可能的促成因素,但认为第二例患者发生CES的病因仍然不明。

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