Department of Anesthesiology, Nihon University School of Medicine, 30-1 Oyaguchi Kamimachi, Itabashi-ku, Tokyo, 173-8610, Japan.
Can J Anaesth. 2011 Jul;58(7):638-641. doi: 10.1007/s12630-011-9505-7. Epub 2011 Apr 26.
To describe a case of complete neurological recovery from cauda equina syndrome lasting ten months following spinal anesthesia with 0.5% hyperbaric bupivacaine and epidural anesthesia with ropivacaine, and to discuss the possible mechanisms involved.
A 79-yr-old man with Paget's disease was scheduled for surgery to remove a skin tumour below his scrotum. He had no history of radicular pain or back pain and no pre-existing neurologic disorder. Surgery was performed with the patient in the supine position. He received 0.5% hyperbaric bupivacaine intrathecally for the procedure and ropivacaine through an epidural catheter for postoperative pain management. After catheter removal, the patient developed urinary retention, fecal incontinence, and perianal hypoesthesia. A lumbosacral magnetic resonance imaging (MRI) revealed no tumour, infarction, degeneration, spinal stenosis, or compression on the cauda equina nerve roots. A diagnosis of cauda equina syndrome was made, and the etiology was thought to be toxicity of bupivacaine either alone or in combination with ropivacaine. After three months, the patient reported some return of sensation at the perianal area, with complete resolution at four months. At the ten-month follow-up visit, the patient had recovered from his urinary retention and fecal incontinence.
This case suggests that spinal anesthesia, even with an ordinary dose of hyperbaric 0.5% bupivacaine, might induce cauda equina syndrome in older patients.
描述一例马尾综合征患者在接受 0.5% 重比重布比卡因脊麻和罗哌卡因硬膜外麻醉后十个月完全恢复神经功能的病例,并讨论可能涉及的机制。
一名 79 岁男性,患有 Pagets 病,拟行阴囊下皮肤肿瘤切除术。他没有神经根痛或背痛病史,也没有预先存在的神经功能障碍。手术时患者取仰卧位。术中给予 0.5%重比重布比卡因鞘内麻醉,术后给予罗哌卡因硬膜外导管镇痛。导管拔除后,患者出现尿潴留、大便失禁和肛周感觉减退。腰骶部磁共振成像(MRI)未见肿瘤、梗死、退变、椎管狭窄或马尾神经根受压。诊断为马尾综合征,病因被认为是布比卡因的单独毒性或与罗哌卡因联合毒性。三个月后,患者报告肛周区域有一些感觉恢复,四个月后完全恢复。在十个月的随访中,患者已从尿潴留和大便失禁中恢复。
本病例提示,即使使用普通剂量的 0.5%重比重布比卡因,老年患者也可能发生马尾综合征。