在健康法国成年受试者中进行肠外镁负荷试验以评估镁状态

Parenteral magnesium loading test in the assessment of magnesium status in healthy adult French subjects.

作者信息

Mazur A, Felgines C, Feillet C, Boirie Y, Bellanger J, Beaufrère B, Gueux E, Rock E, Rayssiguier Y

机构信息

Centre de Recherche en Nutrition Humaine d'Auvergne, Unité Maladies Métaboliques et Micronutriments, INRA, St-Genès-Champanelle, France.

出版信息

Magnes Res. 1997 Mar;10(1):59-64.

PMID:9339839

Abstract

Parenteral magnesium loading test has been proposed as an adequate mean to evaluate magnesium status. However, applied tests vary among different laboratories and standardized procedure is not available. In the present study, we assessed magnesium status in 32 healthy adult French subjects by magnesium loading test using MgCl2 and determination of magnesium concentrations in plasma and erythrocytes. We observed a positive correlation between plasma and erythrocyte magnesium concentrations, but there was no correlation between magnesium retention and basal urinary excretion of magnesium, and plasma or erythrocyte magnesium concentrations.

摘要

胃肠外镁负荷试验已被提议作为评估镁状态的一种适当方法。然而，不同实验室所采用的试验有所不同，且尚无标准化程序。在本研究中，我们通过使用MgCl₂的镁负荷试验以及测定血浆和红细胞中的镁浓度，评估了32名健康成年法国受试者的镁状态。我们观察到血浆和红细胞镁浓度之间呈正相关，但镁潴留与镁的基础尿排泄量以及血浆或红细胞镁浓度之间无相关性。