Guo Y, Majima Y, Hattori M, Seki S, Sakakura Y
Department of Otorhinolaryngology, Mie University School of Medicine, Tsu, Japan.
Arch Otolaryngol Head Neck Surg. 1997 Oct;123(10):1097-100. doi: 10.1001/archotol.1997.01900100073010.
To compare the preoperative and postoperative changes on ciliary surface of maxillary sinus mucosa in patients treated with functional endoscopic sinus surgery.
The maxillary mucosa of both the superolateral wall and the ostium were sampled during the operation and 6 to 12 months (mean duration, 7.6 months) after the operation. Ciliary surface was determined using scanning electron microscopy in combination with an image analyzer and was expressed in terms of ciliary area, which is the percentage of mucosal surface occupied by cilia.
The samples were taken at a hospital-based clinic. An electron microscopic study was performed at Mie University School of Medicine, Mie, Japan.
Sixteen patients (20 maxillary sinuses) undergoing functional endoscopic sinus surgery for treatment of chronic sinusitis.
The mean (+/-SD) ciliary area before the surgery was 60.7%+/-28.8% and 39.9%+/-21.5% in the superolateral wall of the maxillary sinus and the ostium of the maxillary sinus, respectively. The ciliary area of the superolateral wall was significantly higher than that of the ostium (P<.001). The mean (+/-SD) postoperative ciliary area value was 74.3%+/-22.6% in the superolateral wall and 51.3%+/-16.1% in the ostium. These postoperative values were significantly higher than the preoperative values (P<.001).
This study showed that the maxillary sinus mucosa in chronic sinusitis is capable of regeneration, and the damaged ciliated epithelium could return toward normal with the improvement of ventilation and drainage of the maxillary sinus following functional endoscopic sinus surgery.
比较接受功能性鼻内镜鼻窦手术患者上颌窦黏膜纤毛表面的术前和术后变化。
在手术过程中以及术后6至12个月（平均时长7.6个月）对上颌窦外侧壁和窦口的上颌黏膜进行取样。使用扫描电子显微镜结合图像分析仪测定纤毛表面，并以纤毛面积表示，纤毛面积即纤毛占据黏膜表面的百分比。
样本取自一家医院诊所。电子显微镜研究在日本三重县三重大学医学院进行。
16例（20个上颌窦）因慢性鼻窦炎接受功能性鼻内镜鼻窦手术的患者。
上颌窦外侧壁和上颌窦窦口术前纤毛面积的平均值（±标准差）分别为60.7%±28.8%和39.9%±21.5%。上颌窦外侧壁的纤毛面积显著高于窦口（P<0.001）。术后外侧壁纤毛面积平均值（±标准差）为74.3%±22.6%，窦口为51.3%±16.1%。这些术后值显著高于术前值（P<0.001）。
本研究表明慢性鼻窦炎患者的上颌窦黏膜具有再生能力，功能性鼻内镜鼻窦手术后随着上颌窦通气和引流的改善，受损的纤毛上皮可恢复正常。
