Carvalho G A, Nikkhah G, Samii M
Neurochirurgische Klinik, Krankenhaus Nordstadt, Hannover.
Orthopade. 1997 Jul;26(7):621-5. doi: 10.1007/s001320050132.
The occurrence of sever pain is one of the most disabling symptoms after the traumatic lesion of the brachial plexus. Avulsion of one or more cervical roots of the brachial plexus is the main cause of severe pain, known as deafferentation pain. Lesion of the dorsal horn of the cervical spinal cord due to root avulsion may lead to important pathological changes and scarring that are responsible for the induction of pain sensations. Different medical and surgical treatment modalities have been established to relief such pain after brachial plexus injury. In contrast to drug therapy, which usually offers only limited benefit, surgical treatment over the last years has shown positive results. Coagulation of the dorsal root entry zone (DREZ) is one of the most efficient surgical treatments for these patients. Understanding of the pathophysiological changes and different pain mechanisms induced by traumatic injury of the brachial plexus is fundamental for the planning and step-wise treatment of such patients.
严重疼痛的发生是臂丛神经创伤性损伤后最致残的症状之一。臂丛神经一个或多个颈神经根的撕脱是严重疼痛的主要原因,称为去传入性疼痛。神经根撕脱导致颈脊髓背角损伤,可能会引起重要的病理变化和瘢痕形成,从而引发疼痛感。已经确立了不同的药物和手术治疗方式来缓解臂丛神经损伤后的此类疼痛。与通常仅提供有限益处的药物治疗不同,近年来手术治疗已显示出积极效果。背根入髓区(DREZ)凝固术是针对这些患者最有效的手术治疗方法之一。了解臂丛神经创伤性损伤引起的病理生理变化和不同疼痛机制,对于此类患者的治疗规划和逐步治疗至关重要。