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[妊娠期糖尿病——围产期高胰岛素血症与产后发育障碍]

[Gestational diabetes--perinatal hyperinsulinism and postnatal developmental disorders].

作者信息

Briese V, Stiete H, Stiete S

机构信息

Frauenklinik, Universität Rostock, Ernst-Moritz-Arndt-Universität Greifswald.

出版信息

Zentralbl Gynakol. 1997;119(7):324-30.

PMID:9340971
Abstract

The impaired glucose tolerance in pregnancy (IGT) represents an important fact in aetiopathogenesis of insulin dependent diabetes mellitus (IDDM) and non insulin dependent diabetes (NIDDM) as well as obesitas and cardiovascular diseases in context with fetal hyperinsulinism. Prospective studies of diabetic mothers newborns are difficult by reason of health controls in different outpatient departments. The aim of this review is to claim a general glucose screening in pregnancy looking on the development of newborns in later life. In present preventive prospects were not used to decrease the morbidity in diabetes, obesitas and cardiovascular diseases without gestational diabetes screening in pregnancy. The neonatal onset and late morbidity is dependent on the quality of maternal glycemia in pregnancy measured by means of glycosylated hemoglobin and insulin the amniotic fluid.

摘要

妊娠期糖耐量受损(IGT)是胰岛素依赖型糖尿病(IDDM)和非胰岛素依赖型糖尿病(NIDDM)以及肥胖症和心血管疾病病因发病机制中的一个重要因素,且与胎儿高胰岛素血症有关。由于在不同门诊部门进行健康检查,对糖尿病母亲新生儿进行前瞻性研究很困难。本综述的目的是主张在孕期进行常规血糖筛查,以关注新生儿日后的发育情况。在目前的预防前景中,在孕期不进行妊娠糖尿病筛查的情况下,并未采用降低糖尿病、肥胖症和心血管疾病发病率的方法。新生儿发病和晚期发病取决于通过糖化血红蛋白和羊水胰岛素测量的孕期母体血糖水平。

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