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期待疗法与选择性刮宫术治疗自然流产的比较

Expectant management versus elective curettage for the treatment of spontaneous abortion.

作者信息

Hurd W W, Whitfield R R, Randolph J F, Kercher M L

机构信息

Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, USA.

出版信息

Fertil Steril. 1997 Oct;68(4):601-6. doi: 10.1016/s0015-0282(97)00314-2.

Abstract

OBJECTIVE

To determine whether the amount of intrauterine tissue was prognostic of the risk of complications associated with the management of nonviable pregnancies diagnosed in the first trimester before cervical dilatation (termed here impending abortion) with either expectant observation or elective curettage.

DESIGN

Historic cohort study.

SETTING

University Infertility Service.

PATIENT(S): All women with nonviable pregnancies followed by the Division of Reproductive Endocrinology during a 5-year period. The patients were divided into those with significant intrauterine tissue (gestational sac > 10 mm) and those with minimal intrauterine tissue.

INTERVENTION(S): Women either underwent elective curettage or were followed expectantly.

MAIN OUTCOME MEASURE(S): Complication rates.

RESULT(S): In 89 women with minimal tissue, no complications occurred regardless of treatment mode. In 63 women with significant intrauterine tissue, expectant management resulted in more complications (9/24) than elective curettage (1/39). In the expectant group, complications included missed abortion, septic abortion, and incomplete abortion requiring emergency curettage, with one patient requiring a transfusion. In the curettage group one uterine perforation occurred.

CONCLUSION(S): In women with impending abortions and minimal intrauterine tissue, expectant treatment is safe after ectopic pregnancy has been excluded. In patients with significant intrauterine tissue, the risk of complications may be decreased by elective uterine curettage compared with expectant management.

摘要

目的

确定在宫颈扩张前诊断为孕早期不可避免流产(在此称为难免流产)的情况下,宫内组织量是否可预测与期待观察或选择性刮宫处理相关的并发症风险。

设计

历史性队列研究。

地点

大学不孕不育服务中心。

患者

生殖内分泌科在5年期间内随访的所有不可避免流产女性。患者被分为宫内组织量显著(妊娠囊>10mm)和宫内组织量极少两组。

干预措施

女性患者要么接受选择性刮宫,要么进行期待观察。

主要观察指标

并发症发生率。

结果

89例宫内组织量极少的女性,无论采用何种治疗方式均未发生并发症。63例宫内组织量显著的女性,期待治疗组的并发症(9/24)多于选择性刮宫组(1/39)。期待治疗组的并发症包括稽留流产、感染性流产和需急诊刮宫的不全流产,1例患者需要输血。刮宫组发生1例子宫穿孔。

结论

对于难免流产且宫内组织量极少的女性,排除异位妊娠后期待治疗是安全的。对于宫内组织量显著的患者,与期待治疗相比,选择性刮宫可降低并发症风险。

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