Takahashi R, Tachiki K H, Nishiwaki K, Nakamura E, Tateishi T
Folia Psychiatr Neurol Jpn. 1976;30(2):208-18.
Biochemical analyses of brain samples of an Animal Model of Depression indicate the state of motionlessness observed in response to a conditioned stimulus was due to an excess in functional activity of serotonin. An excess functional activity of serotonin may be directly responsible for human depressive illness. This conflicting conclusion to the currently popular theories of serotonin deficiency was discussed with reference to the animal and clinical data in the literature which are consistent with the conclusion.
对一种抑郁症动物模型的脑样本进行生化分析表明，对条件刺激产生的静止不动状态是由于血清素功能活性过高所致。血清素功能活性过高可能直接导致人类抑郁症。结合文献中与该结论一致的动物和临床数据，对这一与当前流行的血清素缺乏理论相矛盾的结论进行了讨论。
