Ernst T, Späth P J, Aebi C, Schaad U B, Bianchetti M G
Department of Paediatrics, University of Bern, Switzerland.
Acta Paediatr. 1997 Sep;86(9):1009-10. doi: 10.1111/j.1651-2227.1997.tb15190.x.
Seventy-seven children with bacterial meningitis were screened for complement deficiency. Both the classical and the alternate pathways were normal in 75 patients. Transiently reduced total haemolytic activity of the classical pathway was documented in a boy with meningococcal meningitis. Total haemolytic activity of both the classical and the alternate pathways were reduced in another patient with pneumococcal meningitis: individual complement components determination indicated predominant activation of the alternate pathway.
对77名患细菌性脑膜炎的儿童进行了补体缺乏筛查。75名患者的经典途径和替代途径均正常。一名患脑膜炎球菌性脑膜炎的男孩出现经典途径总溶血活性短暂降低。另一名患肺炎球菌性脑膜炎的患者经典途径和替代途径的总溶血活性均降低：补体单个成分测定表明替代途径主要被激活。
