[一种新型水溶性醛固酮拮抗剂在外科手术中的应用。早期临床结果]
[Use of a new water-soluble aldosterone-antagonist in surgery. Early clinical results].
作者信息
Nahum M, Ratto G B, Motta G
出版信息
Minerva Med. 1976 Apr 21;67(19):1263-75.
PMID:934482
Abstract
A new i.v., water-soluble aldosterone antagonist (potassium canrenoate) was employed for the first time in a series of patients operated for various forms of abdominal disease. The pharmacological and clinical effects of the drug were constantly reproduced and a marked anti-aldosterone activity was noted. The drug is felt to be specifically indicated in the management of secondary hyperaldosteronism typical of the immediate postoperative period.
摘要
一种新型静脉注射用的水溶性醛固酮拮抗剂（烯睾丙酸钾）首次应用于一系列因各种腹部疾病接受手术的患者。该药物的药理和临床效果不断得到重现，且观察到明显的抗醛固酮活性。该药物被认为特别适用于治疗术后早期典型的继发性醛固酮增多症。
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