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发育性阅读障碍的视觉缺陷理论。

The visual deficit theory of developmental dyslexia.

作者信息

Eden G F, VanMeter J W, Rumsey J M, Zeffiro T A

机构信息

Georgetown Institute for Cognitive and Computational Sciences, Georgetown University Medical Center, Washington, DC 20007, USA.

出版信息

Neuroimage. 1996 Dec;4(3 Pt 3):S108-17. doi: 10.1006/nimg.1996.0061.

Abstract

Dyslexia is an impairment in reading that can result from an abnormal developmental process in the case of developmental dyslexia or cerebral insult in the case of acquired dyslexia. It has long been known that the clinical manifestations of developmental dyslexia are varied. In addition to their reading difficulties, individuals with developmental dyslexia exhibit impairments in their ability to process the phonological features of written or spoken language. Recently, it has been demonstrated with a variety of experimental approaches that these individuals are also impaired on a number of visual tasks involving visuomotor, visuospatial, and visual motion processing. The results of these studies, as well as the anatomical and physiological anomalies seen in the brains of individuals with dyslexia, suggest that the pathophysiology of developmental dyslexia is more complex than originally thought, extending beyond the classically defined language areas of the brain. Functional neuroimaging is a useful tool to more precisely delineate the pathophysiology of this reading disorder.

摘要

阅读障碍是一种阅读能力受损的情况,在发育性阅读障碍中,它可能源于异常的发育过程;在获得性阅读障碍中,则可能由脑部损伤引起。长期以来,人们都知道发育性阅读障碍的临床表现多种多样。除了阅读困难外,发育性阅读障碍患者在处理书面或口头语言的语音特征方面也存在能力缺陷。最近,通过各种实验方法已经证明,这些患者在一些涉及视觉运动、视觉空间和视觉运动处理的视觉任务中也存在障碍。这些研究结果,以及在阅读障碍患者大脑中观察到的解剖学和生理学异常,表明发育性阅读障碍的病理生理学比最初认为的更为复杂,其影响范围超出了大脑中经典定义的语言区域。功能神经影像学是一种有用的工具,可以更精确地描绘这种阅读障碍的病理生理学。

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