Hepburn M J, English J C, Keeling J H
Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234-6200, USA.
Cutis. 1997 Oct;60(4):185-7.
Cutaneous manifestations of petechiae, purpura, and ecchymosis can lead the physician to discover an underlying platelet abnormality. Autoimmune idiopathic thrombocytopenic purpura (AITP) is a diagnosis of exclusion, mediated by a destructive IgG antibody response to the platelets' membrane components. In addition to showing evidence of cutaneous and mucosal bleeding (ie, epistaxis, hematuria), patients with AITP are at an increased risk for systemic lupus erythematosus (SLE). Therefore, it is suggested that patients with AITP be closely monitored for SLE.
瘀点、紫癜和瘀斑的皮肤表现可促使医生发现潜在的血小板异常。自身免疫性特发性血小板减少性紫癜（AITP）是一种排除性诊断，由针对血小板膜成分的破坏性IgG抗体反应介导。除了有皮肤和黏膜出血的证据（如鼻出血、血尿）外，AITP患者患系统性红斑狼疮（SLE）的风险增加。因此，建议对AITP患者密切监测SLE。
