抗-E作为新生儿溶血病的一个病因。

Anti-E as a cause of hemolytic disease of the newborn.

作者信息

Cheepsattayakorn R, Fongsatitkul L, Chotinaruemol S, Mahawongtong M

机构信息

Department of Pathology, Faculty of Medicine, Chiang Mai University, Thailand.

出版信息

J Med Assoc Thai. 1997 Sep;80 Suppl 1:S1-4.

PMID:9347637

Abstract

A case of HDN caused by anti-E antibody is reported. A group A, E-positive, hemoglobin E trait female infant was born from a group A, E-negative, beta-thalassemia/hemoglobin E mother. Hyperbilirubinemia was noted at the first day of life. The DAT was positive. Anti-E was detected in the maternal serum. Jaundice and anemia occurring to the baby were severe enough to require phototherapy intervention for 9 days and 50 ml of group A, E-negative packed red blood cells was transfused. The baby's condition improved. She was discharged at 12 days of age. Follow-up of the baby at 1 year old showed that she was alive and in good health.

摘要

报告了1例由抗-E抗体引起的新生儿溶血病。一名A型、E阳性、血红蛋白E性状的女婴，其母亲为A型、E阴性、β地中海贫血/血红蛋白E患者。出生第一天即发现高胆红素血症。直接抗人球蛋白试验呈阳性。在母亲血清中检测到抗-E。婴儿出现的黄疸和贫血严重到需要进行9天的光疗干预，并输注了50毫升A型、E阴性浓缩红细胞。婴儿病情好转。她在12日龄时出院。对该婴儿1岁时的随访显示，她存活且健康状况良好。