Rapid method for detection of point mutations using mismatch binding protein (MutS) and an optical biosensor.
作者信息
Gotoh M, Hasebe M, Ohira T, Hasegawa Y, Shinohara Y, Sota H, Nakao J, Tosu M
机构信息
Research and Development Department, Pharmacia Biotech KK, Tokyo, Japan.
出版信息
Genet Anal. 1997 Jul;14(2):47-50. doi: 10.1016/s1050-3862(97)00009-0.
PMID:9349940
Abstract
This paper describes a new method for detecting DNA point mutations using a mismatch binding protein. The interactions of mismatches and mismatch binding proteins are detected by the optical biosensor technology based on surface plasmon resonance (SPR).
摘要
Zotero 插件