Zweiker R, Tiemann M, Eber B, Schumacher M, Fruhwald F M, Lipp R, Lax S, Pristautz H, Klein W
Department of Internal Medicine, Karl-Franzens-University of Graz, Austria.
J Intern Med. 1997 Sep;242(3):249-53. doi: 10.1046/j.1365-2796.1997.00198.x.
Pheochromocytoma endures as a life-threatening disorder. In the absence of systemic hypertension, diagnosis may be difficult. We present a 46-year-old normotensive male with a history of presyncope. One of these episodes could be documented, and revealed symptomatic bradycardia suspicious of sinus node arrest. Due to hints of an elevated sympathetic tone (Schellong test, circadian blood pressure pattern without diurnal rhythm) 24-h urinary catecholamine concentrations were measured and found increased. MIBG-scintigraphy and abdominal-computed tomography indicated the location of the pheochromocytoma. After removal of the tumour, no further episodes of presyncopes or bradydysrhythmias were observed.
嗜铬细胞瘤仍然是一种危及生命的疾病。在没有全身性高血压的情况下,诊断可能会很困难。我们报告一名46岁的血压正常男性,有晕厥前病史。其中一次发作有记录,显示有症状性心动过缓,怀疑是窦房结停搏。由于有交感神经张力升高的迹象(Schellong试验,无昼夜节律的昼夜血压模式),测量了24小时尿儿茶酚胺浓度,发现其升高。间碘苄胍闪烁扫描和腹部计算机断层扫描显示了嗜铬细胞瘤的位置。切除肿瘤后,未再观察到晕厥前发作或缓慢性心律失常。