Bayer R C, Chawan C B, Bryan T A
Poult Sci. 1976 May;55(3):1020-5. doi: 10.3382/ps.0551020.
The cecal mucosal changes of a subclinical coccidial (E. tenella) in chickens was studied by scanning electron microscopy. Oral inoculation was used and the mucosal surface of the ceca was studied. A control group from the same hatch of chickens was sampled simultaneously. The ceca from the infected birds was markedly smaller and contained some hemorrhagic areas. The control birds maintained a relatively smooth continuous epithelium throughout the study. During the infection, early fenestration was seen in the epithelium followed by its disruption. The crypts were easily seen as the disease progressed and in some cases the epithelium became denuded. The infective organism may inhibit replacement of degenerating epithelium.
通过扫描电子显微镜研究了鸡亚临床球虫病（柔嫩艾美耳球虫）盲肠黏膜的变化。采用口服接种法并对盲肠黏膜表面进行研究。同时从同一批孵化的鸡中选取一个对照组进行采样。感染组鸡的盲肠明显更小，且有一些出血区域。在整个研究过程中，对照组鸡的上皮保持相对光滑连续。在感染期间，上皮细胞早期出现窗孔，随后上皮细胞遭到破坏。随着病情发展，隐窝容易观察到，在某些情况下上皮细胞会剥脱。感染性生物体可能会抑制退化上皮细胞的更替。
