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人类对体感刺激的短潜伏期皮层反应。一项高分辨率脑电图研究。

Human short latency cortical responses to somatosensory stimulation. A high resolution EEG study.

作者信息

Urbano A, Babiloni F, Babiloni C, Ambrosini A, Onorati P, Rossini P M

机构信息

Institute of Human Physiology, Division of High Resolution EEG (CIMS), University of Rome La Sapienza.

出版信息

Neuroreport. 1997 Oct 20;8(15):3239-43. doi: 10.1097/00001756-199710200-00011.

DOI:10.1097/00001756-199710200-00011
PMID:9351650
Abstract

Human short-latency cortical responses to median nerve stimulation were investigated with a new high resolution electroencephalography technology that markedly enhanced spatial details of somatosensory-evoked potentials (SEPs). Maximum amplitude potentials were estimated over contralateral and/or frontal-mesial scalp regions about 20, 22, 24, 26, 30, 32 and 45 ms following the stimulation. Frontal-lateral P20-N24-N30-P45 and parietal-lateral N20-P24-P30-N45 showed dipolar patterns, whereas frontal-mesial N24-N30-P45 and central-lateral P22-N26-N32-P45 presented no clearcut dipole counterpart. Plausibly, the spatially enhanced frontal-parietal SEP components were generated (tangential dipoles) within the lateral central sulcus cortex, and anticipated the central-lateral and frontal-mesial components generated (radial dipoles) from the crown of the pre- and/or post-central gyri and the supplementary motor area, respectively.

摘要

利用一种新的高分辨率脑电图技术研究了人类对正中神经刺激的短潜伏期皮层反应,该技术显著增强了体感诱发电位(SEP)的空间细节。在刺激后约20、22、24、26、30、32和45毫秒时,估计对侧和/或额中头皮区域的最大振幅电位。额外侧P20-N24-N30-P45和顶外侧N20-P24-P30-N45呈现双极模式,而额中N24-N30-P45和中央外侧P22-N26-N32-P45没有明确的双极对应物。合理地说,空间增强的额顶SEP成分是在中央沟外侧皮层内产生的(切向偶极),并先于分别从中央前回和/或中央后回顶部以及辅助运动区产生的(径向偶极)中央外侧和额中成分。

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