Takashi M, Hibi H, Ohmura M, Sato K, Sakata T, Ando M
Department of Urology, Nagoya University School of Medicine, Japan.
Int J Urol. 1997 Sep;4(5):508-11. doi: 10.1111/j.1442-2042.1997.tb00294.x.
Between 1980 and 1995, we performed a nephrectomy with curative intent on 183 patients with renal cell carcinoma at Nagoya University Hospital. Among these patients, 5 (2.7%) developed renal fossa recurrence (median follow-up, 65 months). We report a case of such a recurrence found 13 years after a nephrectomy for renal cell carcinoma (stage pT3a, pN0, M0). A 62-year-old female presented with a nodule on her back. Computed tomography and magnetic resonance imaging revealed a mass in the right back and retroperitoneum, and a biopsy revealed the tumor to be a renal cell carcinoma. Complete resection was performed, followed by administration of alpha-interferon. The patient is doing well 16 months after the operation. The case illustrates that very long-term follow-up after a nephrectomy is mandatory for patients with perinephric invasion of a renal cell carcinoma due to the risk of renal fossa recurrence.
1980年至1995年间,我们在名古屋大学医院对183例肾细胞癌患者进行了根治性肾切除术。在这些患者中,有5例(2.7%)出现了肾窝复发(中位随访时间为65个月)。我们报告1例肾细胞癌肾切除术后13年出现这种复发的病例(分期为pT3a、pN0、M0)。一名62岁女性背部出现一个结节。计算机断层扫描和磁共振成像显示右背部和腹膜后有一个肿块,活检显示该肿瘤为肾细胞癌。进行了完整切除,随后给予α干扰素治疗。术后16个月患者情况良好。该病例表明,由于存在肾窝复发风险,对于肾细胞癌肾周侵犯的患者,肾切除术后必须进行非常长期的随访。