Bowen J D, Malanga G A
Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, Minnesota, USA.
Spine (Phila Pa 1976). 1997 Oct 15;22(20):2458-63. doi: 10.1097/00007632-199710150-00026.
This is a report of two cases.
To document the occurrence and association of spondylolysis and Arnold-Chiari malformation Type I.
The association of spinal dysraphism has been reported with Arnold-Chiari Type II, but not with Arnold-Chiari Type I.
The senior author was involved in the care of these patients. All medical records, laboratory and radiologic investigations, and related literature were reviewed.
The presence of cephalic and caudal neuropore maldevelopment may be present in various combinations. The presence of spondylolysis, with or without spina bifida occulta, associated with Arnold-Chiari malformation type I and syringohydromyelia, is demonstrated.
In some patients, the presence of spondylolysis may represent a congenital anomaly and may be associated with cephalic neuropore maldevelopment, such as cerebromedullary malformation syndrome (i.e., Arnold-Chiari malformation Type I).
本文报告两例病例。
记录椎弓根峡部裂与Ⅰ型阿诺德 - 基亚里畸形的发生情况及关联。
脊髓发育异常与Ⅱ型阿诺德 - 基亚里畸形有关联的报道已有，但与Ⅰ型阿诺德 - 基亚里畸形的关联尚无报道。
资深作者参与了这些患者的治疗。查阅了所有病历、实验室及影像学检查资料以及相关文献。
头侧和尾侧神经孔发育异常可能以多种组合形式存在。证实了椎弓根峡部裂的存在，无论有无隐性脊柱裂，均与Ⅰ型阿诺德 - 基亚里畸形及脊髓空洞症相关。
在一些患者中，椎弓根峡部裂的存在可能代表一种先天性异常，且可能与头侧神经孔发育异常有关，如脑脊髓畸形综合征（即Ⅰ型阿诺德 - 基亚里畸形）。
