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Specificity of the digoxin radioimmunoassay with respect to dihydrodigoxin.

作者信息

Kramer W G, Bathala M S, Reuning R H

出版信息

Res Commun Chem Pathol Pharmacol. 1976 May;14(1):83-8.

PMID:935656
Abstract

An investigation was conducted to determine the specificity of the digoxin antibody provided in a commercially available radioimmunoassay kit with respect to dihydrodigoxin. Over the concentration range of 0.5 to 8.0 ng./ml. dihydrodigoxin displaced the 125I digoxin derivative from the antibody to a degree that could be significant at clinically observed serum and urine digoxin concentrations.

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