Mathisen G E, Johnson J P
Infectious Disease Service, UCLA-Olive View Medical Center, Department of Medicine, Sylmar, California 91342, USA.
Clin Infect Dis. 1997 Oct;25(4):763-79; quiz 780-1. doi: 10.1086/515541.
The past 20 years have seen major advances in the diagnosis and management of brain abscess, with a corresponding improvement in the survival rates. The advances in radiographic scanning, the availability of new antimicrobials, and the development of novel surgical techniques have all contributed to the decreases in associated morbidity and mortality. The relative rarity of brain abscess and the frequent delays in making the diagnosis render this condition a significant challenge for the clinician. A high index of suspicion is required so that effective therapy can be instituted as soon as possible. Close coordination of care between neurosurgeons and infectious diseases specialists is increasingly important in the complicated management of brain abscess. Adequate abscess drainage and appropriate antimicrobial therapy remain the cornerstones of proper treatment of this condition.
在过去20年里,脑脓肿的诊断和治疗取得了重大进展,生存率也相应提高。放射学扫描技术的进步、新型抗菌药物的出现以及新颖手术技术的发展,都有助于降低相关的发病率和死亡率。脑脓肿相对罕见,且诊断常常延误,这给临床医生带来了重大挑战。需要高度的怀疑指数,以便尽快开展有效的治疗。在脑脓肿的复杂管理中,神经外科医生和传染病专家之间的密切协作愈发重要。充分的脓肿引流和恰当的抗菌治疗仍然是这种疾病正确治疗的基石。