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转移性肺腺癌继发小脑脓肿:病例报告。

Cerebellar abscess secondary to metastatic lung adenocarcinoma: a case report.

机构信息

Department of Medicine, Liaquat National Medical College, Karachi, Pakistan.

Department of Neurosurgery, Liaquat National Hospital and Medical College, Karachi, Pakistan.

出版信息

J Med Case Rep. 2024 Aug 22;18(1):389. doi: 10.1186/s13256-024-04722-w.

Abstract

BACKGROUND

Cerebellar abscesses are rare, life-threatening infections often originating from bacterial sources, while metastatic brain lesions from lung adenocarcinoma are relatively common. However, the coexistence of a cerebellar abscess secondary to metastatic lung adenocarcinoma is exceedingly rare and presents unique diagnostic and management challenges.

CASE PRESENTATION

We report a case of a 35 year-old Pakistani female patient with persistent headaches, nausea, and vertigo, who was found to have a large cerebellar mass with features suggestive of metastatic lung adenocarcinoma. Further investigation revealed a concomitant cerebellar abscess. Surgical excision and broad-spectrum antibiotics were initiated, resulting in a favorable outcome.

CONCLUSION

This case showcases the rarity and complexity of cerebellar abscesses due to metastatic lung adenocarcinoma. Timely intervention, including surgery and targeted therapy, is crucial for successful management. Further research is needed to enhance treatment strategies.

摘要

背景

小脑脓肿是一种罕见的、危及生命的感染,通常由细菌来源引起,而转移性肺癌脑转移瘤则相对常见。然而,继发于转移性肺腺癌的小脑脓肿同时存在极其罕见,并且提出了独特的诊断和管理挑战。

病例介绍

我们报告了一例 35 岁的巴基斯坦女性患者,其持续性头痛、恶心和眩晕,发现有一个大的小脑肿块,具有转移性肺腺癌的特征。进一步的调查显示同时存在小脑脓肿。进行了手术切除和广谱抗生素治疗,结果良好。

结论

本病例展示了由于转移性肺腺癌引起的小脑脓肿的罕见性和复杂性。及时干预,包括手术和靶向治疗,对于成功管理至关重要。需要进一步研究以增强治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f74b/11340145/d429fbb9f114/13256_2024_4722_Fig1_HTML.jpg

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