Javadpour N
Hum Pathol. 1979 Sep;10(5):557-68. doi: 10.1016/s0046-8177(79)80099-4.
During the past several years the development of radioimmunoassay and immunocytochemical techniques to detect small amounts of marker in the sera and cancer cells of cancer patients has made a significant impact on the diagnosis and management of certain cancers. Among these markers alpha-fetoprotein, human chorionic gonadotropin, and pregnancy specific beta-1 glycoprotein have been useful in the staging, detection of recurrence, prognosis, and management of testicular cancer. In this article the recent developments and future perspectives concerning these and other newer markers are discussed.
在过去几年中,用于检测癌症患者血清和癌细胞中少量标志物的放射免疫分析和免疫细胞化学技术的发展,对某些癌症的诊断和治疗产生了重大影响。在这些标志物中,甲胎蛋白、人绒毛膜促性腺激素和妊娠特异性β-1糖蛋白在睾丸癌的分期、复发检测、预后和治疗中发挥了作用。本文讨论了这些标志物以及其他更新标志物的最新进展和未来前景。