Adams M A, Ferraro F R
Western Michigan University, USA.
J Clin Psychol. 1997 Nov;53(7):767-78. doi: 10.1002/(sici)1097-4679(199711)53:7<767::aid-jclp15>3.0.co;2-j.
Acquired immunodeficiency syndrome (AIDS) has become an epidemic in the United States. AIDS dementia complex (ADC) is a neurological dysfunction which has been indicated in 25-90% of AIDS patients, 30-40% of HIV-infected patients, and may be the only presenting manifestation of AIDS. Researchers have investigated many aspects of ADC including clinical features, etiology, epidemiology and prevalence, diagnosis (psychological parameters and laboratory investigations such as CSF, EEG, CT, MRI, PET, and ERP), assessment, neurological features (including neuropsychiatric and neuropsychological measures, and neuropathology), prognosis, and treatment. The research is controversial, complex, and contradictory. A discussion of the many areas of ADC and many hypotheses will be included.
获得性免疫缺陷综合征（艾滋病）在美国已成为一种流行病。艾滋病痴呆综合征（ADC）是一种神经功能障碍，在25%至90%的艾滋病患者、30%至40%的艾滋病毒感染患者中均有发现，并且可能是艾滋病的唯一首发表现。研究人员对ADC的许多方面进行了研究，包括临床特征、病因、流行病学和患病率、诊断（心理参数以及脑脊液、脑电图、计算机断层扫描、磁共振成像、正电子发射断层扫描和事件相关电位等实验室检查）、评估、神经学特征（包括神经精神和神经心理学测量以及神经病理学）、预后和治疗。这项研究存在争议、复杂且相互矛盾。本文将讨论ADC的多个领域以及众多假说。
