Enk A H
Dept of Dermatology, University of Mainz, Germany.
Mol Med Today. 1997 Oct;3(10):423-8. doi: 10.1016/S1357-4310(97)01087-3.
Allergic contact dermatitis is the most common job-related disease of the western world. The only available treatments are avoidance of contact with the allergen and the use of potent corticosteroids. Recently, the role of cytokines in the pathogenesis of this disease has been studied and, besides defining the key molecules and basic cellular immune responses responsible for disease development, these studies might help to develop new therapeutic strategies to target cytokines and thereby try to alter or abrogate ongoing immune reactions.
过敏性接触性皮炎是西方世界最常见的职业相关疾病。现有的唯一治疗方法是避免接触过敏原以及使用强效皮质类固醇。最近，细胞因子在该疾病发病机制中的作用已得到研究，除了确定负责疾病发展的关键分子和基本细胞免疫反应外，这些研究可能有助于开发针对细胞因子的新治疗策略，从而尝试改变或消除正在进行的免疫反应。
