Singh K D, Hamdy S, Aziz Q, Thompson D G
Department of Psychology, Royal Holloway College, University of London, Egham, Surrey, UK.
Electroencephalogr Clin Neurophysiol. 1997 Oct;105(5):345-51. doi: 10.1016/s0924-980x(97)96699-6.
We present a method for the coregistration and topographic mapping of trans-cranial magnetic stimulation (TCMS) data on surface rendered images of the cortex, derived from Magnetic Resonance Images (MRI). We describe the TCMS procedure and the methods used to locate the TCM stimulation sites in the MRI coordinate system, and the algorithms needed to depict the TCMS distribution as a pseudocolour contour map on the cortical surface. The methods are validated using TCMS data from the hand (thenar) and leg (tibialis muscle). The methods used correctly depict the expected motor representations of each of these areas and we therefore propose that this technique may be used as a functional imaging tool in the investigation of cortical function in both normals and patients.
我们提出了一种用于将经颅磁刺激（TCMS）数据与源自磁共振成像（MRI）的皮质表面渲染图像进行配准和地形图绘制的方法。我们描述了TCMS程序以及用于在MRI坐标系中定位TCM刺激位点的方法，以及将TCMS分布描绘为皮质表面伪彩色等高线图所需的算法。使用来自手部（鱼际肌）和腿部（胫骨肌）的TCMS数据对这些方法进行了验证。所使用的方法正确地描绘了这些区域中每个区域预期的运动表征，因此我们建议该技术可作为一种功能成像工具，用于研究正常人和患者的皮质功能。
