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药物性间质性肺病

Drug-induced interstitial lung disease.

作者信息

Limper A H, Rosenow E C

机构信息

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA.

出版信息

Curr Opin Pulm Med. 1996 Sep;2(5):396-404. doi: 10.1097/00063198-199609000-00009.

Abstract

Drugs can have multiple different adverse effects on the lungs, airways, pleura, mediastinum, and the interstitium. Their appearance can mimic other interstitial lung diseases and, for the most part, drug-induced interstitial lung disease is a condition of exclusion rather than a specific entity that can be diagnosed with imaging studies or histology. It is important to be aware of all the potential adverse effects of drugs on the lung in order to recognize the condition and to discontinue the drug as soon as possible, as death will result in many of the situations discussed here if appropriate measures are not taken.

摘要

药物可对肺、气道、胸膜、纵隔和间质产生多种不同的不良反应。其表现可类似于其他间质性肺疾病,并且在很大程度上,药物性间质性肺病是一种排除性诊断,而非可通过影像学检查或组织学确诊的特定疾病。了解药物对肺的所有潜在不良反应非常重要,以便识别病情并尽快停用药物,因为如果不采取适当措施,在此讨论的许多情况下都会导致死亡。

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