Balakumar T, Perry L A, Savage M O
Division of Paediatric Endocrinology, St. Bartholomew's Hospital, London, U.K.
J Pediatr Endocrinol Metab. 1997 Mar-Apr;10(2):227-9. doi: 10.1515/jpem.1997.10.2.227.
We describe a 6 year-old boy who presented with bilateral gynaecomastia, pseudoprecocious puberty and facial features suggestive of Cushing's syndrome. The underlying pathology was a right adrenocortical adenoma which was secreting oestradiol, androgens and cortisol. All the biochemical abnormalities normalised within one week of right adrenalectomy. To our knowledge this combination of hormones produced by an adrenocortical adenoma is particularly unusual.
我们描述了一名6岁男孩,他出现双侧乳腺增生、假性性早熟以及提示库欣综合征的面部特征。潜在病因是右侧肾上腺皮质腺瘤,该腺瘤分泌雌二醇、雄激素和皮质醇。在右侧肾上腺切除术后一周内,所有生化异常均恢复正常。据我们所知,肾上腺皮质腺瘤产生这种激素组合的情况极为罕见。