Suppr超能文献

[苯并咪唑衍生物对病毒感染的影响]

[Effect of benzimidazole derivatives on viral infection].

作者信息

Sorokin A M, Lushnikov A A, Kol'tsov V D

出版信息

Vopr Virusol. 1976 Mar-Apr(2):206-11.

PMID:936579
Abstract

Dibazole and vitamin B12 reduced production of hemagglutinin by influenza A (PR8 and WSN strain) and B-1/73 (Yamagata strain) viruses in chick embryos when inoculated at various intervals after infection. The drugs stimulated interferon production in serum and by blood leukocytes, showing also some protective effect in influenza infection in mice. The necessity of further study of relationships between the chemotherapeutic activity of drugs and their capacity to stimulate nonspecific resistance to infection is emphasized.

摘要

感染后不同时间接种时,地巴唑和维生素B12可降低甲型流感病毒(PR8和WSN株)及乙型流感病毒B-1/73(山形株)在鸡胚中血凝素的产生。这些药物可刺激血清及血液白细胞产生干扰素,对小鼠流感感染也有一定保护作用。强调了进一步研究药物化疗活性与其刺激机体对感染的非特异性抵抗力之间关系的必要性。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验