de Marées H, de Caleya C, Hempelmann G, Sippel R
Z Kardiol. 1976 May;65(5):478-89.
In eight persons central hemodynamic parameters as well as peripheral circulatory parameters were measured before and during spinal anaesthesia (L3/4; 5 ml Carbostesin mit Adrenalin): heart rate, arterial pressure, central venous pressure, peripheral venous pressure, peripheral blood flow, venous capacity (Cv 70) using a venous pressure of 70 mm Hg (lethysmographic method) as well as intravascular basic volume. Intravascular basic volume and the venous capacity are representing total intravascular volume; changes in this parameter- in correlation to a well defind intravenous pressure - give information on the distensibility of capacitance vessels. During spinal anesthesia an increase in resting blood flow of the calf as well as in total blood volume was noted as a result of a decreasing total peripheral resistance and changes in blood distribution (shunting, nutritive blood supply). Intravascular total blood volume in the calf increased from 9.7 +/- 1.0 ml/100 ml to 10.9 +/- 1.1 ml/100 ml, being caused mainly by changes in basic volume not so much by changes in venous capacity. These results may be interpreted as an increase in distensibility of the low pressure vessels during spinal anesthesia.
在八名受试者中,于脊髓麻醉前及麻醉期间(L3/4;5毫升含肾上腺素的卡波卡因)测量了中心血流动力学参数以及外周循环参数:心率、动脉压、中心静脉压、外周静脉压、外周血流量、静脉容量(Cv 70,采用70毫米汞柱的静脉压,通过容积描记法测量)以及血管内基础容量。血管内基础容量和静脉容量代表血管内总容量;该参数的变化与明确的静脉压相关,可提供关于容量血管可扩张性的信息。在脊髓麻醉期间,由于总外周阻力降低以及血液分布改变(分流、营养性血液供应),观察到小腿静息血流量以及总血容量增加。小腿血管内总血容量从9.7±1.0毫升/100毫升增加至10.9±1.1毫升/100毫升,主要是由基础容量的变化而非静脉容量的变化所致。这些结果可解释为脊髓麻醉期间低压血管可扩张性增加。